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  • Hebrew  (2)
  • 2020-2024  (2)
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  • Hebrew  (2)
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  • 1
    Online Resource
    Online Resource
    [Jerusalem] : Magnes Press
    Title: רקוויאם לאספירין הרפואה המדעית על פרשת דרכים
    ISBN: 9789657776995
    Language: Hebrew
    Pages: 1 Online-Ressource
    Year of publication: 2021
    Keywords: Medicine and Health ; Life Sciences
    Abstract: In October 2018, results of a randomized controlled trial showed an excess mortality mainly from cancer, among “healthy” people over the age of 70 who took aspirin, in contrast to many clinical studies previously published. This event was another record in the crisis in scientific medicine that has been unfolding before our eyes in recent decades.In this book the author tries to trace the causes of the shocks that afflict the medical knowledge base, and to offer solutions to strengthen and stabilize it.This book includes four parts. The first part discusses aspirin as a test case for development of clinical research. The second part is devoted to a discussion of the seven foundations of modern clinical research while revealing the pros and cons of each and their relative contribution to the pursuit of scientific truth. In the third part, five groundbreaking discoveries are examined. In each of them, the process that led to the discovery is deciphered, emphasizing the findings making clinical research, on the way from bench to bedside, redundant. In the fourth part the author exposes the rules of the competition among scientist, and determines its impact on the conduct of research and its results
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Online Resource
    Online Resource
    [Jerusalem] : מאגנס = Magnes Press
    Title: האבולוציה של הפרקטיקה הרפואית
    ISBN: 9789657839164
    Language: Hebrew
    Pages: 1 Online-Ressource
    Year of publication: 2023
    Keywords: History ; Medicine and Health ; Life Sciences
    Abstract: In the second half of the twentieth century, the medical community adopted the scientific method as a basis for practice. It seemed that after thousands of years the way was paved for a regulated process: from the laboratory through the clinical trial to the patient's bed. But it soon became clear that the road is neither straight nor continuous. Clinical research only offers unequivocal answers in a few cases. The balance between benefit and risk does not end with a statistical calculation; A significant part of the consideration of the factors that determine the change of medical practice is based on values, worldview and interests. Many factors are involved in the path leading from the laboratory to the patient: scientists, doctors, pharmaceutical and technology companies, politicians, regulators, and at the end of the path stand the patients themselves. Each of these factors uses the means at its disposal to influence the final result - the diagnosis, treatment and follow-up of the patient. The path of progress from the laboratory to the patient is also not continuous: sometimes the intervals between steps are large, sometimes sudden jumps occur after a prolonged period of slowing down and even stopping. Scientific and clinical research depends on the initiative, skills and determination of the researchers, and not a little on coincidences and has no fixed timetables.This book is dedicated to revealing the evolution of medical practice, to identifying fundamental changes in practice and to describing the winding way in which they were accepted and assimilated into the body of medical knowledge and the mutual relationship between the doctor and the patient
    Library Location Call Number Volume/Issue/Year Availability
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